Digoxin, sold under the brand name Lanoxin among others, is a medication used to treat various heart conditions. Most frequently it is used for atrial fibrillation, atrial flutter, and heart failure. Digoxin is taken by mouth or by injection into a vein. DIGITEK® (digoxin) Tablets, USP. DESCRIPTION. DIGITEK (digoxin) is one of the cardiac (or digitalis) glycosides, a closely related group of drugs having in common specific effects on the myocardium. DIGOXIN is used to treat congestive heart failure and heart rhythm problems. The lowest GoodRx price for the most common version of digoxin is around $9.00, 79% off the average retail price of $44.72. Detailed Digoxin dosage information for adults and children. Includes dosages for Congestive Heart Failure and Atrial Fibrillation; plus renal, liver and dialysis adjustments. Professional guide for Digoxin. Includes: pharmacology, pharmacokinetics, contraindications, interactions, adverse reactions and more. What is digoxin? Digoxin is a medicine used to treat certain heart problems such as heart failure. Heart failure results when the heart can’t pump blood well enough to supply the body’s needs. Mechanism. The ECG features of digoxin effect are seen with therapeutic doses of digoxin and are due to: Shortening of the atrial and ventricular refractory periods — producing a short QT interval with secondary repolarisation abnormalities affecting the ST segments, T waves and U waves. Cardiac glycosides have important positive inotropic, neurohormonal, and electrophysiologic actions, which are the basis for its use in two clinical situations: heart failure due to systolic dysfunction, and in certain supraventricular tachyarrhythmias. The ability of digoxin to reduce sympathetic Digoxin is used to treat heart failure, usually along with other medications. It is also used to treat a certain type of irregular heartbeat (chronic atrial fibrillation). - Initial digoxin maintenance dose for patients with heart failure - Inhibitors and inducers of P-glycoprotein drug efflux; CALCULATORS. Calculator: Lean body weight (adult male).